Baclofen is a muscle relaxant used to treat muscle spasms, stiffness, and pain. It belongs to a class of medicines called muscle relaxants and works by reducing nerve signals in the spinal cord that cause muscle tightness.

Baclofen is commonly prescribed for:

• Muscle spasticity due to multiple sclerosis
• Spinal cord injuries or diseases
• Cerebral palsy–related muscle stiffness
• Other conditions causing severe muscle spasms (as determined by a doctor)

Baclofen is available in:

• Tablets (commonly 10 mg, 25 mg)
• Oral liquid (concentrations vary by manufacturer)
• Intrathecal (spinal) injection or pump (used in severe cases under specialist care)

Take baclofen exactly as prescribed by your doctor.

Dosage: Usually taken several times a day, starting with a low dose that is gradually increased. Follow your doctor’s instructions carefully.

Swallow tablets with water. If using liquid, use the measuring device provided.

Do not stop taking baclofen suddenly unless your doctor tells you — this can cause serious withdrawal symptoms such as seizures or hallucinations.

Do not take baclofen if you have:

• Allergy to baclofen or any of its ingredients
• Active stomach ulcer (use with caution)
• Severe kidney disease unless advised by a specialist

Like all medicines, baclofen can cause side effects, although not everyone gets them.

Common side effects:

• Drowsiness or fatigue
• Dizziness
• Nausea
• Weakness in muscles
• Headache

Serious side effects — seek medical attention immediately:

• Hallucinations, confusion, or severe mood changes
• Difficulty breathing or extreme drowsiness
• Seizures
• Severe muscle weakness or inability to move

Baclofen should be used during pregnancy only if clearly needed and prescribed by a doctor.

It may pass into breast milk — discuss with your doctor before breastfeeding.

There is no clear evidence that baclofen affects fertility in men or women.

Some medicines can increase the risk of side effects or alter how baclofen works. Tell your doctor if you take:

• Alcohol or sedatives (can increase drowsiness)
• Sleeping pills or anti-anxiety medications
• Antidepressants
• Antihypertensive medications (may lower blood pressure further)
• Other muscle relaxants