Anastrozole is a medicine used to treat breast cancer in women who have gone through menopause.
It belongs to a class of medicines called aromatase inhibitors, which work by reducing the amount of oestrogen produced in the body.
Lowering oestrogen levels helps slow or stop the growth of certain types of breast cancer that rely on this hormone.
It is commonly prescribed for:
Anastrozole is usually available in the form of:
Take anastrozole exactly as prescribed by your doctor.
Dosage: The usual dose is 1 mg once daily.
It can be taken with or without food, preferably at the same time each day.
Swallow the tablet whole with water. Do not crush or chew it.
Continue taking anastrozole for as long as your doctor recommends — often for several years.
Do not stop taking it without your doctor’s advice, even if you feel well.
Anastrozole should not be used if you have:
Like all medicines, anastrozole can cause side effects, although not everyone gets them.
Common side effects:
Less common or serious side effects:
Tell your doctor if you experience persistent pain, swelling in joints, yellowing of skin or eyes, or unexplained bleeding.
Anastrozole should not be used during pregnancy or breastfeeding.
It is intended only for postmenopausal women.
There is limited information about its effect on fertility, but it may interfere with ovulation in women who have not yet gone through menopause.
Some medicines may interact with anastrozole:
The usual duration is 5 years, but your doctor may adjust this based on your individual treatment plan and response.
No. Anastrozole blocks estrogen, so taking hormone replacement therapy (HRT) would counteract its effect. Always check with your doctor.
Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed one—do not double up.
Weight gain and hair thinning are possible but not guaranteed. Side effects vary between individuals.
Maintain a diet rich in calcium and vitamin D, exercise regularly, and have bone density checks as advised by your doctor.
Moderate alcohol is generally safe, but excessive drinking may worsen side effects like bone thinning or fatigue.
It is primarily prescribed for postmenopausal women with hormone-sensitive breast cancer, but in rare cases may be used in men under specialist supervision.
Medical Disclaimer: This information is provided for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a healthcare professional before starting, stopping, or changing any medication.
Last reviewed: June 2026
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