Alogliptin is an oral medicine used to help control blood sugar levels in adults with type 2 diabetes mellitus.
It belongs to a class of medicines called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors), which work by increasing the levels of hormones (incretins) that help regulate blood sugar.
It helps the body produce more insulin when blood sugar is high and reduces the amount of glucose made by the liver.
Alogliptin is used for:
Alogliptin is usually available in the form of:
Take alogliptin exactly as prescribed by your doctor.
Dosage: The usual adult dose is 25 mg once daily.
It can be taken with or without food, usually at the same time each day.
If you have kidney problems, your doctor may prescribe a lower dose.
Do not stop taking alogliptin without consulting your doctor, even if you feel well — your blood sugar may rise again.
Continue to follow your recommended diet, exercise, and regular blood sugar monitoring plan.
Alogliptin should not be used if you have:
Like all medicines, alogliptin can cause side effects, although not everyone gets them.
Common side effects:
Less common or serious side effects:
Seek medical attention immediately if you experience severe stomach pain, difficulty breathing, or swelling of the face or throat.
There is limited experience with alogliptin use during pregnancy and breastfeeding.
It should only be used if the potential benefits outweigh the risks, as advised by your doctor.
It is not known if alogliptin passes into breast milk.
There is no evidence that alogliptin affects fertility in men or women.
Some medications can interact with alogliptin:
Alogliptin usually begins to lower blood sugar within a few hours, but full effects on overall blood sugar control may take several weeks.
Yes, alogliptin is often prescribed together with metformin to improve blood sugar control. Follow your doctor's dosing instructions.
Take the missed dose as soon as you remember. If it’s near the time of your next dose, skip the missed one. Do not take extra doses.
Alogliptin alone rarely causes low blood sugar, but the risk increases if combined with other diabetes medications like sulfonylureas or insulin.
Moderate alcohol is generally safe, but excessive drinking can affect blood sugar levels. Always monitor your sugar and consult your doctor.
Look out for severe stomach pain, nausea, vomiting, or back pain. If these occur, seek medical attention immediately.
Alogliptin can be used in kidney or heart disease, but doses may need adjustment. Always follow your doctor’s guidance and monitoring.
Medical Disclaimer: This information is provided for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a healthcare professional before starting, stopping, or changing any medication.
Last reviewed: June 2026
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